GLP-1 RECEPTOR AGONIST
In stock
The one that started it all. GLP-1 is the reference compound of the incretin family — a long-acting analogue of the gut hormone that tells the body food has arrived.
Because it's so thoroughly characterized, it's the baseline labs measure everything else against: satiety signalling, glucose regulation, receptor binding. When a metabolic study needs a known quantity, this is usually it.
Keep the sealed vials in the fridge and out of direct light — they’ll hold up for a long time that way. Once a vial is mixed, keep it refrigerated and use it within the window your protocol calls for.
Every batch we sell is tested by an independent U.S. lab before it goes up for sale — that report is the certificate of analysis, and a copy is included with every order. Want the one for your exact vial? Email the lot number printed on the label to [email protected] and we’ll send it over within one business day.
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Also referenced as: GLP-1 receptor agonist · GLP-1 analogue
Glucagon-like peptide-1 is the gut hormone that tells the body food has arrived — released within minutes of a meal, it prompts glucose-dependent insulin secretion and satiety signalling, then vanishes almost immediately as enzymes cut it apart. Our GLP-1 is a long-acting synthetic analogue of that hormone: the same receptor, engineered persistence.
Two modifications do the work. A substitution near the N-terminus blocks the DPP-4 enzyme that destroys native GLP-1, and a fatty-diacid chain partway down the peptide binds serum albumin, turning a two-minute hormone into a compound that stays active for days. This architecture made the GLP-1 class the most-studied peptide family in metabolic science.
GLP-1 is the reference molecule of incretin research. It anchors receptor-binding and internalization assays, glucose-stimulated insulin-secretion work in islet preparations, satiety and food-intake models in rodents, and an enormous comparative literature — when a new incretin design is published, this is the baseline it's measured against.
That maturity is the practical appeal: the receptor pharmacology is thoroughly characterized, assay protocols are published in detail, and results slot into a decades-deep body of work. When a metabolic study needs a known quantity, this is usually it.
Verified at 98.8% purity by HPLC with confirmed CAS identity, supplied lyophilized in 10–50 mg vials with endotoxin held under 0.5 EU/mg. Store the powder at −20 °C away from light; work from reconstituted material kept at 2–8 °C.
Alongside GLP-2T (dual agonist) and GLP-3R (triple agonist), it completes a one-two-three receptor series from a single verified source — a clean design for comparative incretin studies.
The published record runs deeper than any product page should. For the primary literature, browse GLP-1 studies on PubMed. For how every batch we sell is verified, see how we test.
From our research library: How to read a certificate of analysis. · What “research use only” actually means. · The incretin ladder: one, two, three receptors.
No. GLP-1 is supplied strictly for laboratory research. It is not for human or veterinary use, and every order requires agreement to our research-use policy.
No — it's a long-acting analogue. Native GLP-1(7-36) is destroyed by DPP-4 within minutes, which makes it impractical for most study designs. This analogue keeps the receptor pharmacology while resisting that breakdown, which is exactly why the class dominates the literature.
Because everything about it is known. Its receptor kinetics, its downstream signalling and its behaviour in standard models are documented across thousands of papers, so it serves as the fixed point against which newer single-, dual- and triple-receptor compounds are compared.
The current batch is 98.8% pure by HPLC, tested by an independent US laboratory before sale — along with identity confirmation and endotoxin screening below 0.5 EU/mg. The certificate of analysis is included with every order, and the report for any specific vial is available by emailing its lot number.
GLP-1 is available in 10mg, 20mg, 30mg and 50mg vials of lyophilized powder. Quantity discounts apply automatically at checkout.
Keep sealed vials frozen at −20 °C and away from light. Once reconstituted, hold the solution at 2–8 °C and use it within the window your laboratory protocol defines.
